The Half-life of Facts: Why Everything We Know Has an Expiration Date, by Samuel Arbesman
Two websites to take home : devnothink and mendeley
This book has some historian and sociology hues, but first and foremost it is very analytical. Simply so. The parts I particularly like are phase transition and the discussion of 'nice people do tend to win more Nobel".
The book is fairly interdisciplinary. Synthesis seems to be the trend now